Benefits:
- Unique selectivity;
- Effective one-stage cleaning from aggregates and other impurities;
- High physical and chemical stability;
- Simple column packing.
- Method - liquid chromatography
- Functional group - Ca²⁺, PO₄³¯, OH¯, F¯
- Matrix - ceramic hydroxyfluoroapatite (Ca₁₀ (PO₄) ₆ (OH) ₁. ׅ₅ (F) ₀.₅)
- Maximum pressure - 1500 psi (100 bar)
- Dynamic capacity -> 25 mg lysozyme / g sorbent; 25-50 mg / ml IgG at a flow rate of 300 cm / h
- Particle size - 40 microns
- Pore size - 600-800 Å
- Recommended flow rate - 50-1000 cm / hour
- Chemical stability - 1 N NaOH, 6 M urea, 8 M guanidine-HCl, ethanol, methanol, 100% acetonitrile
- Autoclaving conditions - 121 ° C, 20 min in phosphate buffer, pH 7
- pH stability: pH 6.5-14