Principle of operation:
The CGQ BioR sensor has a built-in array of LEDs and photodiodes to emit light and measure backscatter intensity. It is installed on the outside of the bioreactor wall. Depending on the current concentration of biomass inside the bioreactor, when a light beam enters the bioreactor, a certain amount of light is scattered through the vessel wall. When fixing the sensor to the bioreactor wall, a fastening strap is used. The choice of belts of different lengths allows the CGQ BioR sensor to be used with different types and sizes of bioreactors.
Use:
- real-time measurement, documentation of growth kinetics and comparison with earlier batches
- process control when creating make-up profiles
- the use of growth curves to maximize the production of a protein product
- screening of media and bacterial strains to improve the conditions of the bioprocess
- selection of conditions for clones of cells in a short time period
- identifying constraints, limiting factors and pollution at an early stage
- creation of complex make-up profiles
- applicable to a wide range of organisms: bacteria, fungi, yeast, algae
- non-invasive measurements (connecting the sensor to the outer wall of the bioreactor using a special belt)
- the possibility of using double-walled bioreactors with vessels, as well as with old, scratched bioreactors
- high reproducibility of results due to fewer errors in contrast to manual biomass measurement
- the presence of two modes of measurement OD 600 from 0.5 to 500:
- standard (for low cell density) - 521 nm
- high cell density mode - 940 nm
- detector - photodiode
- light source - controlled LED matrix
- sensor size (width x depth x height, mm) - 96 x 82 x 22
- sensor size with LEDs and photodiodes - 20 mm x 20 mm
- monitoring up to 64 bioreactors in parallel on one PC
- easy installation and use with plug and play technology
- intuitive user interface
- quick sensor adjustment
- visualization of measurement results by CGQuant software, as well as their export to Excel for further processing
- the ability to install software on an unlimited number of PCs
- inadmissibility of autoclaving